Btg2 macrophage
WebMay 28, 2024 · Macrophage-derived exosomes (Mφ-Exos) are involved in tumor progression, but its role in glioma is not fully understood. RBP-J is related to … WebB-cell translocation gene 2 (BTG2), the first gene identified in the BTG/TOB gene family, is involved in many biological activities in cancer cells acting as a tumor suppressor. The BTG2 expression is downregulated in many human cancers. It is an instantaneous early response gene and plays important …
Btg2 macrophage
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WebFeb 11, 2024 · Perivascular macrophages, which are resident brain macrophages, originate from the same pool of yolk sac hematopoietic progenitors, migrate to the brain early in development, and self-renew ... WebOct 5, 2024 · IER2 stochastically induces senescence in melanoma cells via the p53–p21 axis. To investigate the impact of constitutive IER2 expression in melanoma, we …
WebNov 15, 2016 · Macrophage activation was impaired when glycolysis was blocked by chemical inhibitors. Remarkably, lactate was found to inhibit LPS-induced glycolysis in … Webcation gene 2 (BTG2) could be targeted by miR-365. BTG2 is a can-cer suppressive gene and C-reactive protein treatment could enhance the human monocyte expression of …
WebJan 12, 2007 · Exposure of macrophages to bacterial products such as lipopolysaccharide (LPS) results in activation of the NF-κB transcription factor, which orchestrates a gene expression programme that underpins the macrophage-dependent immune response. These changes include the induction or repression of a wide range of genes that regulate …
WebDusp2 was suppressed by salubrinal in LPS-activated macrophages as well as PMA/ionomycin-activated T lymphocytes and mast cells. Furthermore, a partial silencing of Dusp2 downregulated IL1β and Cox2, and the inflammatory signs of CAIA mice were significantly suppressed by salubrinal.
WebJan 1, 2015 · JUNB is a key transcriptional modulator of macrophage activation. Activated macrophages are crucial for restriction of microbial infection but may also promote … ra 473WebJun 17, 2024 · BACE-1 is required for generating β-amyloid (Aβ) peptides in Alzheimer’s disease (AD). Here, we report that microglial BACE-1 regulates the transition of homeostatic to stage 1 disease-associated microglia (DAM-1) signature. BACE-1 deficiency elevated levels of transcription factors including Jun, Jund, Btg2, Erg1, Junb, Fos, and Fosb in ... ra 4728WebSep 15, 2024 · In particular, the levels of M2-type macrophages, which are thought to be pro-fibrogenic during tissue repair, decreased evidently. Taken together, this suggests that blocking EMT could halt the related … don\u0027t starve crock potWebMar 13, 2008 · The BTG2 gene is also induced upon several cellular stresses by p53-dependent and p53-independent mechanisms and shows reduced expression in a large … ra 4733WebBtg2 Downregulation Leads to Increased Microglia Proliferation (A) Normalized read count of genes involved in microglia proliferation (Hammond et al., 2024). (B) Representative images of in vitro... don\u0027t starve cyclum puzzlesWebWe observed an obvious positive correlation between BTG2 expression and the infiltrated level of B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and DCs in LUAD, which suggested that high BTG2 expression might up-regulate the abundance of immune-infiltrating cells. ra 4727WebApr 3, 2024 · B-cell translocation gene 2 (BTG2, also called PC3/Tis21) was identified as an anti-proliferative protein regulated by p53 activation [ 14] and was initially described as an immediate early gene induced by growth factors and tumor promoters in PC12 and … ra 4726