Cajaninstilbene acid

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August undefined, 2024

WebJul 15, 2015 · Cajaninstilbene acid, which is isolated from pigeonpea leaves, has shown antibacterial activity. In this study, a series of cajaninstilbene acid derivatives were designed and … Discovery of novel antibacterial agents with new structural scaffolds that combat drug-resistant pathogens is an urgent task. WebAug 1, 2024 · Cajaninstilbene acid and its derivatives ( 13a-13i) were obtained by hydrolysis of 12a-12i. In this way, we accomplished the synthesis of cajaninstilbene acid and its derivatives through a building block in only six steps. The synthesis route is shorter than those previously reported and produces a much higher overall yield [ 11, 13 ].

(PDF) Production and Secretion of Cajaninstilbene Acid in Hairy …

WebSep 1, 2014 · Background/Aims: Cajaninstilbene acid (3-hydroxy-4-prenyl-5-methoxystilben-2 -carboxylic acid, CSA), a natural stilbene isolated from the leaves of Cajanus cajan, has attracted considerable ... WebJan 1, 2012 · acid, CSA), a natural stilbene isolated from the leaves of Cajanus cajan, has attracted considerable attention for its wide range of pharmacological activities. This study investigated whether... huawei mediapad t5 pen

Frontiers Cajaninstilbene Acid Ameliorates …

WebJan 30, 2024 · Finally, we identified the cajaninstilbene acid, a main bioactive stilbene component in MECC, which significantly modulated the LDLR and PCSK9 expression in HepG2 cells. Our current data suggest that the cajaninstilbene acid may contribute to the hypocholesterolemic activity of Cajanus cajan L. leaves. WebNov 16, 2024 · In this study, a synthetic approach to the natural products cajaninstilbene acid (1) and amorfrutins A (2) and B (3) has been developed and was characterized by … WebCajaninstilbene acid protects corticosterone-induced injury in PC12 cells by inhibiting oxidative and endoplasmic reticulum stress-mediated apoptosis. Neurochemistry … huawei mediapad t5 repair

Absorption, Metabolism, and Excretion of Cajaninstilbene Acid

WebCajaninstilbene acid. 2-Hydroxy-4-methoxy-3- (3-methyl-2-butenyl)-6- (2-phenylethenyl)benzoic acid. 2-hydroxy-4-methoxy-3- (3-methylbut-2-en-1-yl)-6- [ (E)-2 … WebPPHRCs were initiated by culturing a high-productive hairy root line (PPHRL II) under the optimal conditions reported previously [10]. Apart from cajaninstilbene acid (separation and purification by our laboratory), all flavonoid standards were provided by Weikeqi Biological Technology Co., Ltd. (Chengdu, China). axalta alestaWebJan 16, 2015 · A common building block for the synthesis of amorfrutin and cajaninstilbene acid derivatives has been developed. The library of synthesized compounds has enabled identification of new nontoxic ligands of peroxisome proliferator-activated receptors (PPAR) and potential inhibitors of the transcriptional corepressor protein NCoR. huawei mediapad t5 prix

"WebJan 12, 2011 · The antioxidant properties, DNA damage protective activities, and xanthine oxidase (XOD) inhibitory effect of cajaninstilbene acid (CSA) derived from pigeon pea leaves were studied in the present work. Compared with resveratrol, CSA showed stronger antioxidant properties, DNA damage protective activity, and XOD inhibition activity. " - Cajaninstilbene acid

Cajaninstilbene acid

WebThe antioxidant properties, DNA damage protective activities, and xanthine oxidase (XOD) inhibitory effect of cajaninstilbene acid (CSA) derived from pigeon pea leaves were studied in the present work. Compared with resveratrol, CSA showed stronger antioxidant properties, DNA damage protective activity, and XOD inhibition activity. The IC50 values … WebDec 28, 2024 · In this study, a synthetic approach to the natural products cajaninstilbene acid (1) and amorfrutins A (2) and B (3) has been developed and was characterized by the Heck reaction, which was used to obtain the stilbene core and a Pinick oxidation to give the O-hydroxybenzoic acid. The biological activities of these compounds against the P ...

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WebNational Center for Biotechnology Information WebNov 14, 2024 · The natural product cajaninstilbene acid (CSA, Fig. 1) has an antibacterial scaffold and we have identified several cajaninstilbene acid derivatives with excellent antibacterial activity against ...

WebMar 8, 2024 · Acetaminophen (APAP)-induced liver injury (AILI) is the main cause of acute liver failure in the developed countries. The present study aimed to evaluate the therapeutic efficacy of cajaninstilbene acid (CSA), a major stilbene compound derived from the leaves of pigeon pea [Cajanus cajan (L.) Millsp.], against AILI.CSA (50, 75 mg/kg, p. o.) was …

WebJun 15, 2015 · The negative-pressure cavitation extraction (NPCE) technique was applied firstly to extract secoisolariciresinol diglucoside (SDG) from flaxseed cakes. The significant extraction parameters were screened by fractional factorial design (FFD). The optimal parameters were determined using the central composite design (CCD) with the two … WebSep 28, 2024 · A facile synthesis of cajaninstilbene acid and its derivatives Synthetic studies towards daphniyunnine B:Construction of AC bicyclic skeleton with two vicinal all carbon quaternary stereocenters.

WebAug 15, 2010 · Cajanuslactone (1), together with pinostrobin (2) and cajaninstilbene acid (3), was isolated from the bioassay-guided fraction of pigeon pea leaves, using a …

WebThe total yield of eight flavonoids (414.95 ± 50.68 μg/g DW) in 42-day-old PPHRCs exposed to 4 h of UV-B radiation increased by 1.49-fold as against control, whereas the yield of cajaninstilbene acid (6566.01 ± 702.14 μg/g DW) in PPHRCs undergoing 10 h of UV-B radiation significantly increased by 2.31-fold over control. huawei mediapad t5 pantallaWebMar 1, 2024 · Cajaninstilbene acid (CSA) promotes mitochondrial biogenesis and mitophagy in APAP-induced liver injury. Animal experiment was identical to that in Figure 1, and liver tissues were excised at 6 ... huawei mediapad t5 price in indiaWebSep 24, 2024 · Cajaninstilbene acid (CSA), a major bioactive stilbene isolated from pigeon pea (Cajanus cajan) leaves, exerted the neuroprotective property in our … axa villa rosaWebFeb 24, 2024 · Cajaninstilbene acid (CSA), an active stilbene isolated from the leaves of pigeon pea (Cajanus cajan), exhibits several bioactivities.To develop CSA as a potential nutraceutical and provide pharmacokinetic foundations for its further in vivo bioactivity studies, this study aims to explore its absorption, metabolism, and excretion … huawei mediapad t5 precio guatemalaWebMar 21, 2024 · Isowighteone (3’-isoprenyl genistein) is a prenylated stilbenoid derivative that exhibits neuroprotective, antibacterial, and anti-inflammatory properties. To establish a bioproduction system for this bioactive compound, hairy root cultures of pigeon pea ( Cajanus cajan (L.) Millsp.) were deve … huawei mediapad t5 romWebMar 1, 2024 · Cajaninstilbene acid (CSA), a main bioactive constituent in pigeon pea leaves, has been reported to exhibit various pharmacological activities, including antioxidative [23], anti-tumor [24], hypoglycemic [5] and antibacterial [26] effects. huawei mediapad t5 sellWebMar 8, 2024 · Cajaninstilbene acid (CSA) is a natural stilbene compound isolated from the leaves of pigeon pea [Cajanus cajan (L.) Millsp.]. The pigeon pea is commonly … axa vitality