WebMar 8, 2024 · Gdf9-Cre transgenic mice were a gift from Dr. Heng-Yu Fan (Yu et al., 2013). To generate Hif1α fl/fl; Gdf9-Cre mice (referred to as Hif1α-cKO), female mice carrying the Hif1α floxed alleles were mated with Gdf9-Cre males (Yu et al., 2013). The Hif1 α fl/fl female mice were used as the control group (referred to as Control). Genotyping for ... WebOocyte-specific deletion of ovarian genes using Cre/loxP technology provides an …
Maternal Ezh1/2 deficiency in oocyte delays H3K27me2/3
WebOvaries from Lkb1 fl/fl and Lkb1 fl/fl ; Gdf9-Cre mice with indicated ages were embedded in paraffin, and serial sections of 8 μm in thickness were prepared and stained with hematoxylin and eosin. WebOct 5, 2024 · Ddx4-Cre and Gdf9-Cre knock-in mice were maintained on a C57BL/6 J background and obtained from Nanjing Biomedical Research Institute of Nanjing University (Nanjing, China). Dicer conditional null ... greg tilley\u0027s bossier city la
011062 - GDF9-iCRE Strain Details - The Jackson Laboratory
WebDec 30, 2024 · we generated oocyte-specific knockout mouse models to study the roles of LONP1 during oocyte development and maturation. In mice with Gdf9-Cre-mediated oocyte-specific Lonp1 knockout, ovarian and early oocyte development appeared normal from birth until 3 weeks of age, as these mice showed a similar number of follicles to that of the … WebDec 24, 2024 · Because Gdf9 is not expressed in granulosa cells and DDB1 expression was unaltered in these cells in Gdf9-cre transgenic mice, this finding suggests that CRL4 DCAF1 functions in oocytes to control granulosa cell expansion and survival in a non-autonomous manner (Yu et al., 2015b). WebOct 23, 2024 · Gdf9-Cre transgenic mice were a gift from Dr. Qing-Yuan Sun at Guangdong Second Provincial General Hospital . All mice described above were maintained on the C57BL/6 J background. Mice lacking Mettl3 in oocytes (referred to as Mettl3 Gdf9 cKO) were generated by crossing Mettl3 flox/flox mice with Gdf9-Cre mice. fiche equideow code html